Department of Human Genetics

UNIVERSITY of DEBRECEN

András Penyige M.Sc., Ph.D.

András Penyige M.Sc., Ph.D.
Associate Professor
Phone: +36 52 512 900 /65764
E-mail: penyige@med.unideb.hu
Personal data:

Dr. András Penyige
Associate Professor
University of Debrecen, Faculty of Medicine, Department of Human Genetics
4032 Debrecen, Egyetem tér 1., Hungary
Telephone: +36-52/512-900, 65764
E-mail: penyige@med.unideb.hu
Office: LSB 2.403

Education:

Studied biology and chemistry at Lajos Kossuth University of Sciences and Arts Debrecen, 1973-1979. (University thesis: Preparation of embryonic fate map in early developmental mutants of Drosophila melanogaster; prepared at the Biological Research Center of Hungarian Academy of Sciences, Szeged; Institute of Insect Genetics; supervisor: Janos Szabad, Ph.D.,D.Sc.).

Scientific degree/title:

Ph.D. (1986). Title of doctorate thesis: Isolation of a streptomycin-containing Park-nucleotide complex from the fermentation broth of S. griseus protoplasts. (Published in Antimicrobial Agents and Chemotherapy)

Language skills:

English 

Positions/workplaces:

1979-98, Research associate, Institute of Biology, University Medical School Debrecen, 
1998-1999, Research associate, Albert Szentgyörgyi University Szeged, Institute of Medical Biology
1999- Associate Professor, University of Debrecen, Fac. of Medicine, Institute of Human Genetics

Experience abroad:

1986-1988: at University of Wisconsin, Madison, Dept. of Bacteriology in the laboratory of Prof. J.C. Ensign as a post-doctoral fellow.
1992-1993: Universite de Liege, Centre d,Ingeniere des Proteins, Belgium
1994-1995: National Food Research Institute, Biomolecular Transfunction Laboratory, Tsukuba, Japan, research associate.
2003: SGM Fellowship, University of East Anglia, School of Biological Sciences, Norwich, UK,
2004-2005: Lahey Hospital and Medical Center, Burlington, MA. USA
 
Memberships:

Hungarian Society of Microbiology
European Society of Human Genetics
Hungarian Society of Human Genetics
 
Awards:

Acknowledgment of the Minister of Health for excellent teaching activities (1986, Budapest).
 
Fields of interest:

1. Investigation of the mode of action of b-lactam antibiotics, the function and biochemical characterization of of the b-lactamase gene in Streptomyces strains. Testing of new b-lactam compounds. Study of regulation and induction of autolytic enzymes in Streptomyces strains.
2. Study of the regulation of differentiation, antibiotic production and spore formation in Streptomyces griseus, including: the mechanism of action of A-factor, GTP-binding proteins, the physiological role of protein ADP-ribosylation and Ca2+-binding proteins in Streptomyces.
3. Study of the role of G-proteins during aging in human lymphocytes and neutrophyl granulocytes.
4. Genetic association studies in complex human diseases (COPD, IBD, exome sequence analysis).

Scientometric data:

Impact factor:                   82,970
Citations:                             286

 

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